The Germinative Epithelium of Sheep Vibrissae and Wool Follicles Has Extensive Proliferative Potential but Is Dependent on the Dermal Papilla

    January 2012 in “ International journal of trichology ”
    Nicholas W Rufaut, Nicole T Goldthorpe, Anthony J Craven, Olivia Wallace, Janet E. Wildermoth, A. J. Nixon
    TLDR Sheep hair follicle cells can grow a lot but need the dermal papilla to do so.
    The study concluded that the germinative epithelium of sheep vibrissae and wool follicles exhibited significant proliferative potential, which was heavily reliant on the presence of the dermal papilla. This dependency highlighted the critical role of dermal papilla cells in regulating the growth and regeneration of hair follicles. The findings underscored the importance of epithelial-mesenchymal interactions in hair follicle biology and could have implications for understanding hair growth and developing treatments for hair loss.
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