Diagnosis of Childhood and Adolescent Growth Hormone Deficiency Using Transcriptomic Data

    February 2023 in “ Frontiers in Endocrinology
    Terence Garner, Ivan Wangsaputra, Andrew Whatmore, Peter Clayton, Adam Stevens, Philip Murray
    TLDR Childhood growth hormone deficiency can be accurately diagnosed using gene expression data and random forest analysis.
    The study demonstrated that childhood growth hormone deficiency (GHD) could be diagnosed with high accuracy by combining gene expression (GE) data with random forest analysis. This approach provided a reliable method for identifying GHD in children and adolescents, potentially improving diagnostic precision compared to traditional methods.
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