Global Trends in Platelet-Rich Plasma Research: A Bibliometric Review with Hotspot Visualization

April 2026 in “ Medicine ”

Zhe Zhang, Shiyao Zhao, Peng Hei

platelet-rich plasma PRP androgenetic alopecia dermatology regenerative medicine

This bibliometric review analyzes global research trends in platelet-rich plasma (PRP) from 2020 to 2024 using VOSviewer software. The study finds that the number of scientific papers on PRP has increased annually, with the United States leading in publications. Key research areas include orthopedics, tissue engineering, chronic wound healing, neurogenic pain, dermatology, androgenetic alopecia, and reproductive medicine. The study highlights ligament, cartilage, and joint repair as current research hotspots, while future trends are expected to focus on neurogenic pain, androgenetic alopecia, reproductive medicine, and regenerative medicine.

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research Novel Versus Modified Platelet-Rich Plasma Therapy for Hair Loss Treatment: A Systematic Review and Meta-Analysis

May 2023

Stand-alone PRP therapy effectively increases hair density for hair loss treatment.

Evaluation of Platelet-Rich Plasma Plus Basic Fibroblast Growth Factor Combined With Minoxidil in the Treatment of Androgenetic Alopecia: A Randomized Controlled Trial

research Evaluation of Platelet-Rich Plasma Plus Basic Fibroblast Growth Factor Combined With Minoxidil in the Treatment of Androgenetic Alopecia: A Randomized Controlled Trial

May 2023 in “Journal of Cosmetic Dermatology”

Using platelet-rich plasma, basic fibroblast growth factor, and minoxidil together significantly increases hair count and growth rate in people with hair loss.

research Safety and Efficacy of ALRV5XR in Men with Androgenetic Alopecia: A Randomised, Double-Blinded, Placebo-Controlled Clinical Trial

3 citations , September 2021 in “EClinicalMedicine”

ALRV5XR effectively increases hair density in men with androgenetic alopecia without adverse effects.

research Platelet-Rich Plasma: New Performance Understandings and Therapeutic Considerations in 2020

848 citations , October 2020 in “International Journal of Molecular Sciences”

PRP shows promise in treating joint and spine issues, but translating lab results to humans is challenging.

research Platelet-Rich Plasma Injections in the Treatment of Male Androgenetic Alopecia: A Randomized Placebo-Controlled Crossover Study

9 citations , September 2019 in “Journal of Cosmetic Dermatology”

PRP injections improve hair density in male hair loss.

research Wound Healing: A Cellular Perspective

1160 citations , November 2018 in “Physiological Reviews”

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Platelet-Rich Plasma in Combination With 5% Minoxidil Topical Solution and 1 mg Oral Finasteride for the Treatment of Androgenetic Alopecia: A Randomized Placebo-Controlled, Double-Blind, Half-Head Study

research Platelet-Rich Plasma in Combination With 5% Minoxidil Topical Solution and 1 mg Oral Finasteride for the Treatment of Androgenetic Alopecia: A Randomized Placebo-Controlled, Double-Blind, Half-Head Study

19 citations , May 2017 in “Dermatologic Surgery”

Combining platelet-rich plasma with 5% minoxidil solution improves hair regrowth in androgenetic alopecia patients.