TLDR Rat hair follicle cells can produce and release various glycosaminoglycans over time.
In 1981, a study on rat dermal tissue cultures, which included a significant number of hair follicle cells, demonstrated the production of glycosaminoglycans. These glycans were found both in cell aggregates and in material released from the cells. The study identified several glycosaminoglycan species, including hyaluronic acid, dermatan sulfate, chondroitin-4-sulfate, heparin, and heparan sulfate-C, with hyaluronic acid and dermatan sulfate being secreted into the culture medium. It was observed that the synthesis and sulfation patterns of these glycosaminoglycans changed over time in culture.
3 citations
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June 1979 in “The Journal of Dermatology” Glycosaminoglycan levels peak early in hair growth and decrease as the cycle progresses.
9 citations
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January 1975 in “The Histochemical Journal” Dog hair follicles contain important molecules that may affect hair growth.
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March 2022 in “Polymers” Substances from Ascidian tunics might help treat hair loss as effectively as Minoxidil.
8 citations
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September 2016 in “Pediatric dermatology” People with Mucopolysaccharidoses often have skin problems like thick skin and extra hair, and recognizing these can help diagnose and treat the condition early.
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November 2014 The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
January 2023 in “Biomaterials Science” Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.
2 citations
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December 2023 in “Advanced science” Glycosaminoglycans help heal wounds but aren't yet ready for clinical use.
