The HAIR-AN Syndrome: A Case Report

January 1995

Özcan Balat, Alper Sönmez, Kaya Saraç, Mustafa Şenol

HAIR-AN syndrome insulin resistance acanthosis nigricans hyperandrogenism hirsutism secondary amenorrhea oral contraceptives spironolactone birth control pills Aldactone

TLDR Treatment improved symptoms in a woman with HAIR-AN syndrome.

The HAIR-AN Syndrome, affecting about 5% of hirsute women, was characterized by insulin resistance, elevated insulin levels, acanthosis nigricans, and hyperandrogenism. In this case report, a 21-year-old woman with secondary amenorrhea, hirsutism, and hyperpigmented skin changes was treated with oral contraceptives and spironolactone. After 9 months, she showed significant clinical and hormonal improvement.

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community AA and Hirsutism but T levels are normal

in Female 4 upvotes 5 years ago

27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

community Claim: Insulin resistance increases the enzyme that creates DHT and affects the liver's ability to control hormones

in Research/Science 4 upvotes 6 months ago

Insulin resistance may increase DHT production, contributing to hair loss, and addressing it through diet, nutrients, and natural DHT blockers like saw palmetto and pumpkin seed oil could help reverse hair loss. Some users prefer medications like finasteride for more effective results.

community Insulins impact on androgen levels

in Research/Science 17 upvotes 4 years ago

Controlling insulin levels through intermittent fasting and a low glycemic diet may improve hair quality by reducing androgens. It's important to maintain proper nutrition, including electrolytes and protein, during fasting.

community Female male-pattern AGA- seeking help

in Female 1 upvotes 2 years ago

A female with male-pattern hair loss (AGA) is seeking help after unsuccessful treatments with spironolactone and supplements, and is considering oral minoxidil and finasteride despite concerns about medication side effects. She has ruled out hormonal birth control and PRP/PRFM, and is looking into further medical advice due to abnormal lab results.

community Interesting new publication suggesting that MPB should be assessed as a early warning sign for type-2 diabetes.

15 upvotes 8 years ago

Male pattern baldness (MPB) may be an early warning sign for type 2 diabetes due to its association with insulin resistance. Treatments discussed include testosterone therapy and finasteride, which affects hormone levels related to hair loss and insulin sensitivity.

community What treatment helps diffuse hair thinning from insulin resistance?

in Treatment 1 upvotes 2 years ago

The individual is experiencing hair loss due to insulin resistance (IR) and is seeking advice. They are currently using a keto diet, supplements, exercise, and plan to add metformin to their regimen.

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The Hirsute Woman: Challenges in Evaluation and Management

research Effects of a Low-Dose Desogestrel-Ethinylestradiol Combination on Hirsutism, Androgens, and Sex Hormone Binding Globulin in Women with Polycystic Ovary Syndrome

53 citations , January 1985 in “Acta obstetricia et gynecologica Scandinavica”

Low-dose oral contraceptives reduced hair growth and testosterone levels in women with polycystic ovary syndrome.