Hair Cortisol Analysis: An Update on Methodological Considerations and Clinical Applications

Hair cortisol analysis was explored as a non-invasive method to measure long-term cortisol levels, offering potential applications in clinical diagnostics and research. The method involved the incorporation of cortisol into hair, allowing retrospective quantification. It was particularly useful in diagnosing conditions like Cushing syndrome, stress-related disorders, and cardiovascular diseases. The analysis extended to animal models and post-mortem applications, providing insights into stress and health conditions. Despite its promise, the technique required further standardization and optimization for broader clinical use.