Validation and Reference Ranges of Hair Cortisol Measurement in Healthy Children

    January 2014 in “ Hormone Research in Paediatrics ”
    Gerard Noppe, Elisabeth F. C. van Rossum, Jan W. Koper, Laura Manenschijn, G.J. Bruining, Yolanda B. de Rijke, Erica L T van den Akker
    TLDR Hair cortisol levels in children increase with age but are not affected by gender, puberty, or hair care.
    The study aimed to establish reference ranges for hair cortisol concentrations (HCC) in healthy children and assess the effects of age, gender, puberty, and hair care. Involving 128 children aged 4-14 years, the study found that HCC increased with age, with mean values of 5.0, 5.8, 6.8, and 8.5 pg/mg for ages 4-5, 6-7, 8-9, and 10-14 years, respectively. Children aged 4-7 had significantly lower HCC compared to adults. No influence of gender, puberty, or hair care on HCC was observed. The study concluded that HCC can be reliably measured in children, with reference ranges increasing with age.
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