Relationships Between Hair-Follicle Afferent Terminations and Glutamic Acid Decarboxylase-Containing Boutons in the Cat's Spinal Cord
April 1987
in “
Brain Research
”
TLDR Hair-follicle nerves in cats' spinal cords can be inhibited by GABA-related connections.
The study investigated the neurotransmitter identity in axon terminals associated with hair-follicle afferent boutons in cats' spinal cords. By using intra-axonal labeling and immunocytochemistry, it was found that boutons containing glutamic acid decarboxylase, which synthesizes the inhibitory neurotransmitter γ-aminobutyric acid (GABA), formed synaptic-like associations with hair-follicle afferent boutons. This indicated that hair-follicle afferent axons could be presynaptically inhibited.