From Hair to Pancreas: Transplanted Hair Follicle Mesenchymal Stem Cells Express Pancreatic Progenitor Cell Markers in a Rat Model of Acute Pancreatitis

January 2021 in “ PubMed ”

Xiaoli Sun, Yang Gao, Haoyuan Chen, Ningning Yang, Yichi Zhang, Qi Liu, Yanan Jiang, Shizhu Jin

hair follicle-derived mesenchymal stem cells HF-MSCs mesenchymal stem cells stem cells pancreatic progenitor cell markers

TLDR Hair follicle stem cells may help treat acute pancreatitis by reducing inflammation and aiding regeneration.

The study investigated the use of hair follicle-derived mesenchymal stem cells (HF-MSCs) as a treatment for acute pancreatitis (AP) in a rat model. HF-MSCs were transplanted into rats with AP, where they migrated to the damaged pancreas, expressed pancreatic progenitor cell markers, reduced inflammation, and promoted regeneration. The results indicated that HF-MSC transplantation could be a promising therapeutic approach for treating AP.

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