Hair Loss and 5-Aminosalicylic Acid Enemas

November 1982 in “ Annals of Internal Medicine ”

Preeta K. Kutty

5-aminosalicylic acid sulfasalazine ulcerative proctitis ulcerative colitis hair loss mesalamine

TLDR 5-aminosalicylic acid enemas may cause hair loss.

The document reported two cases of accelerated hair loss associated with the use of 5-aminosalicylic acid enemas for treating ulcerative proctitis. This was notable because 5-aminosalicylic acid, unlike its precursor sulfasalazine, was believed to be free of side effects. The cases involved a 24-year-old man with idiopathic distal ulcerative colitis, suggesting a potential side effect of hair loss from this treatment, which was previously considered unlikely.

View this study on acpjournals.org →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community 5 months in to Min/Fin Oral 1.3mg treatment. Hair-loss slowed/stopped

in Is this regrowth? 10 upvotes 1 week ago

Hair loss has slowed or stopped after 5 months of daily oral minoxidil and finasteride treatment, with ketoconazole shampoo used twice a week. Noticeable thickening is observed, especially on the mid scalp.

community 5 months on finasteride and minoxidil

in Progress Pictures 231 upvotes 2 weeks ago

A user shared progress after 5 months on oral finasteride (1mg) and minoxidil (2.5mg), noting improvements despite minimal temple growth. They experienced shedding initially but reported no side effects, and others shared similar experiences and additional treatments like hair serums.

community 5 weeks tretinoin, severe shed and thinning.

in Minoxidil 3 upvotes 2 weeks ago

The user has been using minoxidil for 5 years and finasteride for 7 months, with recent addition of tretinoin cream causing significant hair shedding. Other users suggest the shedding indicates effectiveness and recommend continuing tretinoin use.

community 5 months on Minoxidil + 1mg Fin + Consistent Scalp Massage

in Progress Pictures 16 upvotes 2 weeks ago

Using minoxidil, finasteride, and consistent scalp massage improved hair growth. Adding pepper and garlic daily also contributed to better results.

community 5 months of topical Minoxidil. Don’t give up hope

in Progress Pictures 315 upvotes 2 weeks ago

A user shared their positive experience with topical Minoxidil for hair regrowth, noting thicker and fuller hair without using Finasteride due to concerns about side effects. Many commenters advised adding Finasteride to maintain gains, warning that Minoxidil alone might not prevent future hair loss.

community 5 Months Post-Finasteride Shed: No Regrowth and Worse Hair Volume

in Finasteride 106 upvotes 3 weeks ago

The user experienced hair loss and used a topical minoxidil and finasteride solution, which initially halted hair fall and increased thickness. After switching to oral finasteride, they experienced significant shedding without regrowth, leaving them worse off than before.