Hair Loss Associated With <scp>IL</scp> ‐17 and <scp>IL</scp> ‐23 Inhibitors: A Systematic Review
May 2026
in “
International Journal of Dermatology
”
This systematic review investigates the association between hair loss and the use of IL-17 and IL-23 inhibitors, which are commonly used in the treatment of autoimmune diseases. The review highlights that while these inhibitors are effective in managing conditions like psoriasis, they may have adverse effects, including hair loss. The study compiles data from various clinical trials and case reports, indicating that hair loss is a potential side effect, although the exact mechanism remains unclear. The findings suggest that clinicians should be aware of this possible adverse effect and monitor patients accordingly. The review emphasizes the need for further research to understand the underlying mechanisms and to develop strategies to mitigate this side effect.