Hair Manganese as a Marker of Cardiometabolic Status Rather Than Coronary Artery Disease Severity—An Exploratory Pilot Study

This exploratory pilot study investigated the relationship between hair manganese (Mn) levels and cardiometabolic status in 80 patients undergoing coronary angiography. The study found no significant association between hair Mn concentration and coronary artery disease (CAD) severity or acute coronary syndrome (ACS) subtypes. However, a modest inverse correlation between hair Mn and body mass index (BMI) was observed, suggesting a potential link between Mn homeostasis and cardiometabolic regulation. The study concludes that while hair Mn is not a marker of CAD severity, it may have implications for cardiometabolic status, warranting further investigation in larger studies.