Complete Hair Regrowth in a Patient With Severe Alopecia Areata Treated With Deucravacitinib

    Shin Shen Yong, Bevin Bhoyrul
    TLDR Deucravacitinib led to full hair regrowth in a severe alopecia areata patient.
    A patient with severe alopecia areata experienced complete hair regrowth after being treated with deucravacitinib, a selective TYK2 inhibitor. This result is notable because TYK2 is not typically associated with the pathogenesis of alopecia areata, indicating that TYK2 inhibition may have immunomodulatory effects. The case highlights the importance of investigating new pathways and off-target mechanisms for treating alopecia areata.
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