Hamamelis Virginiana L. in Skin Care: A Review of Its Pharmacological Properties and Cosmetological Applications

Hamamelis virginiana L. (witch hazel) is a medicinal plant with significant dermatological applications due to its bioactive compounds like phenolic acids and flavonoids, which provide antimicrobial, anti-inflammatory, antioxidant, and wound-healing properties. These benefits have been supported by various in vitro and in vivo studies, along with limited clinical trials. The plant's extracts are effective against bacteria, fungi, and some viruses, and they help modulate cytokine expression and NF-κB signaling to reduce inflammation, enhance skin regeneration, and protect against UV damage and pollution. The review suggests that H. virginiana holds promise for future therapeutic use in skin care.