Hormonal Therapy in Dermatology

January 2001 in “ Dermatologic clinics ”

James C. Shaw

hormonal therapy androgens acne hirsutism androgenetic alopecia medications evaluations hormone treatment male hormones hair loss hair growth

TLDR Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

The document from January 1, 2001, discussed the use of hormonal therapy in dermatology, particularly for conditions influenced by androgens such as acne, hirsutism, and androgenetic alopecia. It highlighted that while hormonal therapy is one of the options for treating acne, it stands as the sole medical treatment for hirsutism and the most promising option for medically managing androgenetic alopecia. The article covered the underlying reasons for using hormonal treatments, the patient demographics, the conditions treated, the most commonly used medications, and the necessary evaluations before initiating treatment.

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research The Effects of Finasteride on Scalp Skin and Serum Androgen Levels in Men with Androgenetic Alopecia

65 citations , October 1999 in “Journal of The American Academy of Dermatology”

Finasteride effectively reduces hair loss by decreasing androgen levels.

research Treatment of Hair Loss

370 citations , September 1999 in “The New England Journal of Medicine”

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

research Comparison of Finasteride and Flutamide in the Treatment of Idiopathic Hirsutism

32 citations , July 1999 in “Fertility and Sterility”

Finasteride and flutamide both reduce hair growth, but finasteride has fewer side effects.

research Finasteride in the Treatment of Men with Frontal Male Pattern Hair Loss

187 citations , June 1999 in “Journal of The American Academy of Dermatology”

Finasteride effectively treats frontal hair loss with few side effects.

research Treatment of Hirsutism: Comparisons Between Different Antiandrogens with Central and Peripheral Effects

75 citations , March 1999 in “Fertility and sterility”

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.

research Finasteride in the Treatment of Men with Androgenetic Alopecia

581 citations , October 1998 in “Journal of The American Academy of Dermatology”

Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.

research Beneficial Effect of Spironolactone on Androgenic Alopecia

20 citations , December 1997 in “Clinical Endocrinology”

Spironolactone may help reduce hair loss in androgenic alopecia.

research Comparison of Finasteride Versus Spironolactone in the Treatment of Idiopathic Hirsutism

76 citations , December 1997 in “Fertility and Sterility”

Finasteride reduces hair growth better, but spironolactone has more side effects.

research Testosterone Concentrations and Oligomenorrhea in Women with Acne

6 citations , November 1997 in “International Journal of Dermatology”

Women with acne and irregular periods had higher active testosterone levels, which could suggest the usefulness of antiandrogen treatment.

Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

416 citations , September 1997 in “Journal of Investigative Dermatology”

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

research Hirsutism

67 citations , January 1997 in “Lancet”

Hirsutism is when women have too much hair growth, often due to a bit more androgen hormones and sensitive skin.

research Antiandrogen Therapy in Dermatology

32 citations , November 1996 in “International Journal of Dermatology”

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up

research Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up

75 citations , November 1996 in “Fertility and Sterility”

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia

143 citations , October 1996 in “Dermatologic Clinics”

Too much androgen can cause hair loss; finasteride may help.

research Antiandrogen And Hormonal Treatment Of Acne

38 citations , October 1996 in “Dermatologic Clinics”

Certain hormone treatments can improve acne and related conditions in women.

research Finasteride in the Treatment of Hirsutism: New Therapeutic Perspectives

50 citations , July 1996 in “Fertility and Sterility”

Finasteride effectively treats hirsutism in women, but more research needed for long-term results.

research The Role of Oral Contraceptives in the Treatment of Hyperandrogenic Disorders

57 citations , January 1995 in “The American journal of medicine”

Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.

research Comparison of Flutamide and Spironolactone in the Treatment of Hirsutism: A Randomized Controlled Trial

165 citations , February 1994 in “Fertility and Sterility”

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

research Comparison of Sequential Cyproterone Acetate/Estrogen Versus Spironolactone/Oral Contraceptive in the Treatment of Hirsutism

68 citations , May 1991 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

Both cyproterone acetate and spironolactone effectively reduce hair growth in women with hirsutism.

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130 citations , September 1990 in “Journal of the American Academy of Dermatology”

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

research Oral Spironolactone Therapy for Female Patients with Acne, Hirsutism, or Androgenic Alopecia

101 citations , January 1985 in “British Journal of Dermatology”

Spironolactone is effective for treating acne, hirsutism, and androgenic alopecia in women with few side effects.