High-Performance Liquid Chromatographic Determination of α-Tocopheryl Nicotinate in Cosmetic Preparations

    A Baruffini, Ersilia De Lorenzi, C. Gandini, M. Kitsos, Gabriella Massolini
    TLDR The document concludes that a fast, accurate method to measure vitamin E derivative in cosmetics was developed.
    The document described a study from 1992 that developed a reversed-phase high-performance liquid chromatographic (HPLC) method to determine α-tocopheryl nicotinate (α-TN) in cosmetic preparations, using α-tocopheryl acetate as an internal standard. α-TN was noted for its ability to accelerate blood circulation and stimulate hair follicle cells, making it a common ingredient in cosmetics. The HPLC method was characterized as rapid, precise, and specific.
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