Immunological and Histological Studies of Different Concentrations of Rosmarinus Officinalis and Thymus Vulgaris Extracts on Thymus Gland of Chick Embryos

This study examined the effects of rosemary and thyme extracts on the thymus gland and immune markers in chick embryos using 160 fertilized eggs divided into 8 groups. High concentrations of these extracts caused damage to thymic tissue and reduced cell density. Immunologically, high thyme concentration decreased IgM levels, while high rosemary concentration and mixed groups decreased IgG levels. IL-10 levels initially decreased but increased by day 20. The findings suggest that while rosemary and thyme have potential benefits, their high concentrations can induce inflammation and negatively impact embryonic development.