Immunological Skin Diseases

The chapter discussed various immunological skin diseases in pigs, including urticaria, bullous pemphigoid, alopecia areata, and porcine ulcerative dermatitis syndrome. Urticaria was described as a rare, variably pruritic, and edematous skin disorder with potential immunologic or nonimmunologic causes such as insects, infections, and medications. Bullous pemphigoid was noted as an extremely rare autoimmune disease in adult Yucatan minipigs, involving IgG autoantibodies targeting collagen XVII. Alopecia areata was identified as a very rare autoimmune dermatosis, where anagen hair follicle antigens are targeted by autoimmune responses.