In Vitro Effects of the Phytocomplex TrichoTech on Human Fibroblasts: Proliferative Potential and Effects on Gene Expression of FGF-7 and FGF-10

January 2017 in “ Journal of Cosmetics, Dermatological Sciences and Applications ”

Fernando Barcellos do Amaral, Maira Jardim, Valéria Maria de Souza Antunes, Luis Felipe Gomes Michelin, Bárbara Anaís Rodrigues dos Santos, Christiano Marcelo Vaz Barbosa, Daniel Gonsales Spíndola, Cláudia Bincoletto, Carlos Rocha Oliveira

TrichoTech phytocomplex essential oils human fibroblasts fibroblast growth factor-7 FGF-7 fibroblast growth factor-10 FGF-10 hair growth regulation cell cycle proliferation wound healing skin repair dermatological use trichological use fibroblasts hair growth

TLDR TrichoTech™ may help hair growth and skin repair by increasing fibroblast growth and activity.

In 2017, a study was conducted on the effects of TrichoTech™, a phytocomplex derived from essential oils, on human fibroblasts, which are cells involved in hair growth regulation. The study found that TrichoTech™ stimulated fibroblast proliferation in a dose-dependent manner, and increased the expression of fibroblast growth factor-7 (FGF-7) and fibroblast growth factor-10 (FGF-10) genes, which can promote cell cycle and proliferation and potentially rescue hair loss. The compound also demonstrated wound healing activity, suggesting potential benefits for skin repair. These findings suggested that TrichoTech™ may have potential applications in promoting hair growth and skin repair, and could contribute to the development of new bioactive phytocomplexes for dermatological and trichological use.

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