Innovative microneedle-integrated hydrogels: a promising strategy for diabetic foot ulcer management

Microneedle-integrated hydrogels present a promising strategy for managing diabetic foot ulcers (DFUs), which are severe complications in diabetic patients due to factors like chronic inflammation and vascular impairment. These hydrogels offer advantages such as minimally invasive application, high drug loading capacity, and controlled release, making them effective in promoting ulcer healing. The review discusses their structural characteristics and drug delivery capabilities, while also addressing current research challenges and future development directions to enhance clinical applications.