Integumentary System: Structure and Function
January 2024
in “
Toxicologic Pathology
”
TLDR The skin protects the body, helps heal wounds, stores energy, and supports health.
The integumentary system, primarily composed of the epidermis, dermis, and hypodermis, serves as a multifaceted barrier and immune organ. The epidermis, with its keratinocyte layers, provides a defense against the external environment and maintains moisture homeostasis. The dermis, rich in collagen, offers structural strength and supports wound healing through its vasculature. The hypodermis, mainly adipose tissue, cushions and stores energy. Additionally, skin adnexa like sweat glands and hair follicles contribute to protection and physiological responses. The skin's complex microbiome plays a crucial role in health, with alterations potentially leading to various pathologies.