Intradermal Injections of 10% Glucose for Scalp Hair Regrowth: A Randomized, Evaluator-Blinded Pilot Study

July 2026 in “ Aesthetic Plastic Surgery ”

Kyu‐Ho Yi, Olena Sydorchuk, Suyeon Lee, Mariya Sobchyshyn, Tae-Hyun Kim, S. Lee, Sijun Park, Yoon Chang-Il, Lee Kyu-Eun

intradermal injections 10% glucose non-cross-linked hyaluronic acid NHA androgenetic alopecia terminal hair density hair shaft diameter glucose hyaluronic acid

TLDR The glucose and NHA combination shows promise for hair regrowth.

This pilot study evaluated the effectiveness and safety of intradermal 10% glucose combined with non-cross-linked hyaluronic acid (NHA) for hair regrowth in 40 adults with androgenetic alopecia. Participants were divided into two groups, receiving either the glucose+NHA treatment or NHA alone over five sessions. The glucose+NHA group showed a significant increase in terminal hair density (+19.3 hairs/cm²) compared to the NHA group (+6.2 hairs/cm²), with a notable between-group difference of 13.1 hairs/cm² (p < 0.001). Additionally, the glucose+NHA group had a greater increase in hair shaft diameter (+12.8%) and higher responder rates (74% vs. 26%). Adverse events were mild and transient, indicating a favorable short-term safety profile. The study concludes that the glucose+NHA combination is promising for hair regrowth, suggesting the need for further research with larger and longer trials.

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