Intratesticular Platelet-Rich Plasma Application to Improve Testicular Development, Hemodynamics, and Testosterone in Male Lambs

This study investigated the effects of intratesticular platelet-rich plasma (PRP) on testicular development in male lambs, focusing on testosterone levels, testicular morphometry, and hemodynamics. Over 10 months, 16 lambs received PRP injections, while 16 controls received saline. Results showed that the PRP group had significantly higher testicular blood flow, scrotal thickness, and testicular length compared to controls, with a lower resistance index in Doppler ultrasonography (p<0.05). Variations in platelet counts and growth factor levels were also noted. The findings suggest that early PRP administration may slightly benefit testicular development due to growth factors in PRP.