Evaluating the Safety and Efficacy of Intense Pulsed Light with Radiofrequency in US Patients with Hidradenitis Suppurativa: A Split-Body Study

November 2020 in “ Journal of the American Academy of Dermatology ”

Alexis B. Lyons, Raheel Zubair, Angela P. Miller, Indermeet Kohli, Iltefat Hamzavi

intense pulsed light radiofrequency hidradenitis suppurativa Dermatology Life Quality Index Hurley Staging-Physician Global Assessment Hidradenitis Suppurativa Clinical Response International Hidradenitis Suppurativa Severity Score System IPL RF HS DLQI HSPGA HiSCR IHS4

TLDR Intense pulsed light with radiofrequency showed mixed results in improving quality of life for hidradenitis suppurativa patients, with no clinical improvements.

This study evaluated the safety and efficacy of intense pulsed light (IPL) with radiofrequency (RF) in treating hidradenitis suppurativa (HS) in the US. Two patients with Hurley Stage II and III HS received IPL+RF treatments on one half of their body every 2 weeks for a total of 10 sessions. The results showed mixed outcomes in patient-reported quality of life, with one patient experiencing a 3-point improvement and the other a 1-point worsening in the Dermatology Life Quality Index (DLQI). However, there were no improvements in clinical outcomes such as Hurley Staging-Physician Global Assessment (HSPGA), Hidradenitis Suppurativa Clinical Response (HiSCR), or the International Hidradenitis Suppurativa Severity Score System (IHS4). No adverse events were reported, but the study suggested that larger studies were needed to further assess the treatment's safety and efficacy.

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