TLDR Irish dermatologists use JAK inhibitors for alopecia areata but want standardized treatment guidelines.
A survey of 124 Irish dermatologists revealed that 90% have experience using Janus kinase inhibitors (JAKi) for treating alopecia areata (AA), with baricitinib being the most common first choice. The study highlights the variability in treatment practices due to the lack of global guidelines, with 95% of respondents expressing the need for standardized guidelines. Despite the impressive efficacy of JAKi, challenges remain, such as high relapse rates post-treatment cessation and the inability to predict patient response. The survey's low response rate (16.9%) and small sample size limit its generalizability, but it provides valuable insights into current practices and the demand for standardized treatment protocols.
August 2024 in “JAMA Dermatology” Continuous baricitinib is needed to keep hair regrowth in severe alopecia areata.
63 citations
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July 2024 in “Journal of the American Academy of Dermatology” Deuruxolitinib effectively promotes hair regrowth in adults with alopecia areata.
1 citations
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February 2024 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Baricitinib effectively promotes long-term hair regrowth in alopecia areata patients.
4 citations
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January 2024 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Baricitinib and ritlecitinib are recommended for severe alopecia areata, with other treatments available off-label.
227 citations
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April 2023 in “The Lancet” Ritlecitinib effectively treats alopecia areata and is well-tolerated.
191 citations
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May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.