The Associations Between Irregular Breakfast and Late-Night Snacking With Metabolic Dysfunction-Associated Steatotic Liver Disease

This study involving 32,030 participants from the Kailuan cohort found that irregular breakfast consumption and late-night snacking are associated with an increased risk of metabolic dysfunction-associated steatotic liver disease (MASLD). Participants who skipped breakfast and snacked late at night had the highest risk, with a hazard ratio of 1.52. The study suggests that maintaining regular eating patterns could reduce the risk of MASLD, with factors like dietary quality, smoking, physical activity, and waist circumference also influencing risk. The research emphasizes the importance of consistent meal timing for metabolic health and was supported by the Capital Health Research and Development of Special Fund and Peking University International Hospital Research Grant.