Adverse Reaction to Isotretinoin: Alteration of the Hair Shaft Structure

    January 2022 in “ Surgical & Cosmetic Dermatology
    Rodrigo Lousada, Edilbert Pellegrini Nahn-Júnior, Hudson Dutra Rezende, Liana Moura de Almeida, Ana Paula Moura de Almeida, Maria Fernanda Reis Gavazzoni Dias
    TLDR Isotretinoin can rarely cause hair to grow curly.
    The document reported a rare case of a patient treated with isotretinoin for acne vulgaris who experienced changes in hair texture, specifically new growing curly hair. While changes in hair shape, color, and texture were known to occur during therapy with oral retinoids, modifications in hair fiber curvature induced by isotretinoin were extremely rare.
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