Italian National Registry of Alopecia Areata: An Epidemiological Study of 699 Italian Patients

May 2024 in “ Italian Journal of Dermatology and Venereology ”

Bianca Maria Piraccini, Luca Rapparini, Federico Quadrelli, Aurora Alessandrini, Francesca Bruni, Stephano Cedirian, Francesca Pampaloni, Emanuela Marcelli, Barbara Bortolani, Enrico Giampieri, Giuseppe Gallo, Francesca Torrelli, Nadia Sciamarrelli, Pietro Quaglino, Carlo Tomasini, Stefania Barruscotti, Francesca Ambrogio, Caterina Foti, Michele Picciallo, Gemma Caro, Alfredo Rossi, Giovanni Pellacani, Lorenzo Ala, Maria Cristina Acri, Laura Diluvio, Enrico Matteini, Luca Bianchi, Giuseppe Argenziano, Graziella Babino, Elisabetta Fulgione, Laura Gnesotto, Andrea Sechi, Luigi Naldi, F. Tassone, Ketty Peris, Giacomo Caldarola, Raffaele Dante Caposiena, Giulia Bazzacco, Iris Zalaudek, Maria Giovanna Vastarella, Mariateresa Cantelli, Angela Patrì, Federica Dall’Oglio, Francesco Lacarrubba, Giuseppe Micali, Alessandro Fraghì, Valeria Boccaletti, Angelo Valerio Marzano, Mauro Barbareschi, Martina Silvio, Emanuele Vagnozzi, Maria Concetta Fargnoli, Chiara Caponio, Laura Atzori, Silvia Sanna, Jasmine Anedda, Claudio Feliciani, Maria Beatrice De Felici Del Giudice, Ilaria Scandagli, Francesca Prignano, Franco Rongioletti, Antonio Podo Brunetti, Gianmarco D Bigotto, Anna Maria Offidani, Oriana Simonetti, Serena Lembo, Annunziata Raimondo, Riccardo Balestri, Tommaso Ioris, Paolo Gisondi, Francesco Bellinato, Emanuele Trovato, Élisa Cinotti, Manuela Papini, Michela Cicoletti, Monica Corazza, Michela Starace

alopecia areata epidemiological study traditional treatments chronic-relapsing nature quality of life new therapies AA

TLDR Alopecia areata is hard to manage and affects quality of life.

The study on the Italian National Registry of Alopecia Areata involved 699 Italian patients and aimed to evaluate the epidemiological data of those with alopecia areata (AA). The registry serves as a model for recording detailed information on the disease's course, associated conditions, and response to traditional treatments. The findings confirm that AA is a challenging condition to manage due to its unpredictable and often chronic-relapsing nature, significantly impacting patients' quality of life. The registry has proven to be an effective tool for standardizing data collection and monitoring new therapies.

View this study on dx.doi.org →

Discuss this study in the Community →

Research cited in this study

18 / 18 results

research European Expert Consensus Statement on the Systemic Treatment of Alopecia Areata

4 citations , January 2024 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Baricitinib and ritlecitinib are recommended for severe alopecia areata, with other treatments available off-label.

research Real-World Treatment Patterns Among Patients With Alopecia Areata in the USA: A Retrospective Claims Analysis

1 citations , August 2023 in “Acta dermato-venereologica”

Corticosteroids are the most common treatment for alopecia areata, but many patients need better options.

research Comorbid Conditions Associated With Alopecia Areata: A Systematic Review and Meta-Analysis

51 citations , July 2023 in “American Journal of Clinical Dermatology”

research Two Phase 3 Trials of Baricitinib for Alopecia Areata

148 citations , March 2022 in “The New England Journal of Medicine”

Baricitinib was effective in treating alopecia areata in two major trials.

research New Insights into Alopecia Areata During COVID-19 Pandemic: When Infection or Vaccination Could Play a Role

7 citations , February 2022 in “Journal of Cosmetic Dermatology”

COVID-19 infection or vaccination may influence the development of alopecia areata, a type of hair loss.

research New Onset of Alopecia Areata in a Patient with SARS-CoV-2 Infection: Possible Pathogenetic Correlations

32 citations , March 2021 in “Journal of cosmetic dermatology (Print)”

COVID-19 infection may trigger alopecia areata in some patients.

research Italian Guidelines in Diagnosis and Treatment of Alopecia Areata

37 citations , December 2019 in “Giornale italiano di dermatologia e venereologia”

The Italian guidelines offer advice for diagnosing and treating alopecia areata based on expert opinion and limited clinical trial evidence.

research Minoxidil for Patchy Alopecia Areata: Systematic Review and Meta-Analysis

20 citations , March 2019 in “Journal of The European Academy of Dermatology and Venereology”

Minoxidil effectively and safely treats patchy hair loss, but more research needed.

research Comorbidities in Alopecia Areata: A Systematic Review and Meta-Analysis

100 citations , July 2018 in “Journal of The American Academy of Dermatology”

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

research Nail Changes in Alopecia Areata: An Update and Review

45 citations , January 2018 in “International Journal of Dermatology”

Nail problems are common in people with alopecia areata, often leading to cosmetic and functional issues, but more research is needed for treatment guidelines.

research Alopecia Areata: Treatment Options and Efficacy

182 citations , December 2017 in “Journal of the American Academy of Dermatology”

Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.

research Alopecia Areata: Overview and Insights from January 2018

290 citations , December 2017 in “Journal of The American Academy of Dermatology”

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

research British Association of Dermatologists’ Guidelines for the Management of Alopecia Areata 2012

218 citations , April 2012 in “British Journal of Dermatology”

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

research Investigative Guidelines for Alopecia Areata

66 citations , May 2011 in “Dermatologic therapy”

Guidelines help design better trials to compare alopecia areata treatments.

research Histopathology of Alopecia Areata, Acute and Chronic: Why Is It Important to the Clinician?

43 citations , May 2011 in “Dermatologic Therapy”

Recognizing the different stages of alopecia areata is crucial for accurate diagnosis and treatment.

research Efficacy And Safety Of A New Clobetasol Propionate 0.05% Foam In Alopecia Areata: A Randomized, Double-Blind Placebo-Controlled Trial

114 citations , October 2006 in “Journal of the European Academy of Dermatology and Venereology”

The new clobetasol propionate foam is effective and safe for treating alopecia areata.

research Clobetasol Propionate 0.05% Under Occlusion in the Treatment of Alopecia Totalis/Universalis

146 citations , July 2003 in “Journal of the American Academy of Dermatology”

Clobetasol propionate ointment can help some people with total hair loss regrow hair.

research The Pattern and Profile of Alopecia Areata in Singapore: A Study of 219 Asians

275 citations , November 2002 in “International Journal of Dermatology”

Alopecia areata mainly affects young people and has significant psychological impacts, especially in males.