This Month in JAAD Case Reports: October 2023—Central Centrifugal Cicatricial Alopecia in Black Men

Central centrifugal cicatricial alopecia (CCCA) is predominantly a condition affecting Black women, but recent observations have identified its occurrence in Black men as well. While traditionally linked to specific hair care practices, such as the use of hot combs and tight hairstyles, these associations lack definitive evidence. A genetic component has been identified, with mutations in the PADI3 gene, which plays a role in hair shaft formation, being linked to CCCA. This highlights the need for further research into the genetic and environmental factors contributing to CCCA in both men and women.