Keloid Formation and Skin Complications in Patients Treated With Isotretinoin and Undergoing Skin-Related Procedures

This study reviewed 34 studies involving 1563 patients to assess the necessity of delaying skin procedures after isotretinoin treatment for acne vulgaris. The findings suggest that there is insufficient evidence to support delaying procedures like laser hair removal, fractional lasers, chemical peels, and dermabrasion. However, fully ablative lasers, mechanical dermabrasion, and ablative radiofrequency are not recommended during isotretinoin use. It is advised to use a lower dose of isotretinoin for all skin procedures, particularly aggressive ones. Further research is needed to determine the safety and optimal timing for these procedures.