Different Patterns of Lichen Planus in Three Members of One Family

This study examines three siblings from an Iranian family, each diagnosed with different variants of Lichen Planus (LP): Lichen Planus Pigmentosus, Lichen Planopilaris, and Frontal Fibrosing Alopecia. The siblings, aged 50 to 60, showed symptoms like facial pigmentation, scalp erythema, and hairline recession. The study suggests potential genetic and environmental factors in LP's pathogenesis, as such familial multivariant cases are previously unreported. Treatments varied, including topical corticosteroids and finasteride, with all siblings achieving remission at a 9-month follow-up. The findings indicate a need for further research into the genetic components of LP.