February 2024 in “Scientific reports” Four genes are potential markers for hair loss condition alopecia areata, linked to a specific type of cell death.
1 citations
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December 2023 in “International journal of molecular sciences” miR-199a-3p controls hair growth and is linked to alopecia areata.
4 citations
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January 2023 in “Skin Appendage Disorders” This study investigated the expression levels of long noncoding RNA HOTAIR and microRNA-205, as well as their relationship with transforming growth factor β1 (TGF-β1) in patients with alopecia areata (AA). The case-control study included 50 AA patients and 50 healthy controls. Results showed that lncRNA HOTAIR was significantly downregulated, while miRNA-205 and TGF-β1 were significantly upregulated in AA patients. These findings suggested that the altered expression of these molecules could play a role in the pathogenesis of AA and might serve as potential therapeutic targets for treatment.
May 2022 in “Cardiovascular Toxicology” 290 citations
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August 2021 in “Clinical Reviews in Allergy & Immunology” JAK inhibitors show promise for treating alopecia areata, but more research is needed.
10 citations
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February 2019 in “Journal of Cellular Biochemistry” Specific RNA patterns are linked to alopecia areata.
84 citations
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February 2015 in “Experimental Dermatology” PPARγ is crucial for skin health but can have both beneficial and harmful effects.
110 citations
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December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.
421 citations
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April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.