Loose Anagen Hair Syndrome: Take a Closer Look!

May 2022 in “ British Journal of Dermatology ”

Cassandre Pottier, Sébastien Eymieux, Emmanuelle Blanchard-Laumonnier, Juliette Robert, A. Maruani, Sophie Leducq

loose anagen hair syndrome anagen hairs inner root sheaths minoxidil Rogaine

TLDR The girl's hair condition improved on its own in 24 months.

A 35-month-old girl exhibited symptoms of loose anagen hair syndrome, characterized by hair lightening and reduced growth over 1 year. Examination showed hair of unequal length, a positive and painless hair pull test, and specific microscopic features such as longitudinal grooves and uniquely shaped bulbs. The condition typically involves anagen hairs lacking inner root sheaths. In this case, spontaneous resolution occurred within 24 months, with normal hair recovery, although minoxidil was suggested as a potential future treatment.

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research Low-Dose Oral Minoxidil Improves Global Hair Density and Length in Children with Loose Anagen Hair Syndrome

9 citations , December 2020 in “British Journal of Dermatology”

Low-dose oral minoxidil increases hair thickness and length in children with a hair disorder called Loose Anagen Hair Syndrome.

research Abnormal Inner Root Sheath of the Hair Follicle in the Loose Anagen Hair Syndrome: An Ultrastructural Study

31 citations , December 2010 in “Journal of the American Academy of Dermatology”

Loose anagen hair syndrome is caused by structural abnormalities in the hair follicle's inner root sheath.