The Effectiveness of Medicated Hair Tonic Containing Royal Jelly Extract

March 2024 in “ Journal of Society of Cosmetic Chemists of Japan ”

Ryo Takahashi, Ryo Tsubokawa, Chizuru Fujikura, Nobuaki Okumura, Ayanori Yamaki, Norihiro SHIGEMATSU, Yoshikazu Yonei

royal jelly extract IGF-1 FGF-7 anagen ratio scalp moisture content RJ extract

TLDR The hair tonic with royal jelly extract improved hair growth and scalp health.

The study on a medicated hair tonic containing royal jelly (RJ) extract involved 27 participants and demonstrated significant improvements in hair growth and scalp health over 24 weeks. The tonic increased hair number, anagen ratio, and scalp moisture content, with subjective evaluations also noting enhanced hair and scalp quality. RJ extract was found to boost the expression of IGF-1 and FGF-7, important for maintaining the hair growth phase. Despite the absence of a control group, the findings suggest that the RJ extract-containing tonic could be a promising treatment for hair thinning and loss, offering benefits without the side effects of conventional medications. Further research is needed to isolate RJ's effects and confirm its efficacy.

View this study on jstage.jst.go.jp →

Discuss this study in the Community →

Research cited in this study

11 / 11 results

research Scalp Biophysical Characteristics in Males with Androgenetic Alopecia: A Comparative Study with Healthy Controls

12 citations , May 2021 in “Clinical Interventions in Aging”

Men with androgenetic alopecia have oilier and less hydrated scalps, especially in sensitive areas.

research Cepharanthine: An Update of Its Mode of Action, Pharmacological Properties, and Medical Applications

125 citations , May 2019 in “Phytomedicine”

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

research Interventions for Female Pattern Hair Loss

21 citations , May 2016 in “The Cochrane library”

Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.

research Androgenetic Alopecia: An Update

88 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

Minoxidil and finasteride effectively treat hair loss.

research Alterations in Hair Follicle Dynamics in Women

26 citations , January 2013 in “BioMed Research International”

Hormonal changes after childbirth and menopause can lead to women's hair loss and facial hair growth, with a need for better treatments.

Adenosine Increases Anagen Hair Growth And Thick Hairs In Japanese Women With Female Pattern Hair Loss: A Pilot, Double-Blind, Randomized, Placebo-Controlled Trial

research Adenosine Increases Anagen Hair Growth And Thick Hairs In Japanese Women With Female Pattern Hair Loss: A Pilot, Double-Blind, Randomized, Placebo-Controlled Trial

33 citations , December 2008 in “Journal of Dermatology”

Adenosine lotion improves hair growth and thickness in women with hair loss.

research Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells

66 citations , February 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.

Androgen-Inducible TGF-β1 from Balding Dermal Papilla Cells Inhibits Epithelial Cell Growth: A Clue to Understanding Paradoxical Effects of Androgen on Human Hair Growth

research Androgen-Inducible TGF-β1 from Balding Dermal Papilla Cells Inhibits Epithelial Cell Growth: A Clue to Understanding Paradoxical Effects of Androgen on Human Hair Growth

190 citations , October 2002 in “The FASEB journal”

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

research Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis

520 citations , February 2001 in “Journal of Clinical Investigation”

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

research The Biology of Hair Care

41 citations , October 2000 in “Dermatologic clinics”

Better hair care products are needed to protect against grooming and chemical damage.

research Vascular Endothelial Growth Factor Is an Autocrine Growth Factor for Hair Dermal Papilla Cells

135 citations , January 1996 in “Journal of Investigative Dermatology”