Managing Menopausal Skin Changes: A Narrative Review of Skin Quality Changes, Their Aesthetic Impact, and the Role of Hormone Replacement Therapy
August 2025
in “
Journal of Cosmetic Dermatology
”
TLDR Hormone replacement therapy can improve menopausal skin quality, but it's not recommended just for skin due to limited evidence.
The narrative review examines the impact of menopause on skin quality, primarily due to decreased estrogen levels, resulting in reduced collagen, elasticity, and moisture. Hormone Replacement Therapy (HRT) shows potential in improving skin quality by enhancing collagen synthesis, elasticity, and hydration, but its use is not recommended solely for skin improvement due to inconsistent findings and lack of robust trials. While some studies report benefits, others, like the KEEPS study, do not find significant improvements in skin conditions. The review emphasizes the need for more comprehensive studies, including diverse demographics, to better understand HRT's role in skin aging. It also suggests that combining HRT with aesthetic treatments could enhance outcomes for postmenopausal women, highlighting the importance of addressing menopausal skin concerns to improve quality of life.