Metabolic Syndrome in Greek Women with Polycystic Ovary Syndrome: Prevalence, Characteristics, and Associations with Body Mass Index. A Prospective Controlled Study

    November 2015 in “ Archives of Gynecology and Obstetrics ”
    Giannoula Kyrkou, E Trakakis, Achilleas Attilakos, Periklis Panagopoulos, Charalampos Chrelias, Anastasios Papadimitriou, V. Vaggopoulos, Eleni Alexiou, Georgios Mastorakos, Aikaterini Lykeridou, Dimitrios Kassanos, Vasiliki Papaevangelou, Nikolaos Papantoniou
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    TLDR Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.
    In a study involving 230 Greek women with polycystic ovary syndrome (PCOS) and 155 age-matched healthy controls, it was found that the prevalence of metabolic syndrome (MetS) was significantly higher in the PCOS group at 12.6%, compared to 1.9% in the control group. Women with PCOS also had higher body mass index (BMI) and were more likely to be overweight or obese, with 42.6% of the PCOS group being overweight or obese compared to 21.9% of the control group. The study concluded that Greek women with PCOS are at an increased risk for cardiovascular disease and type 2 diabetes mellitus (T2DM), emphasizing the importance of periodic screening and lifestyle interventions. However, the study had a limitation due to the relatively small sample size.
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