TLDR Microneedle patches could replace injections but need more development for better use in medicine.
Microneedle (MN) patches emerged as a promising alternative for drug delivery, offering minimally invasive and controlled release methods. They facilitated transdermal delivery by creating micro-sized channels in the skin, enhancing permeability for various molecules. Different types of MNs, such as solid, dissolving, and smart MNs, were developed to address specific drug delivery challenges. MNs showed potential in treating metabolic, autoimmune disorders, and in vaccine delivery, with studies demonstrating increased hair density in alopecia areas and tumor suppression in cancer models. Despite their promise, challenges like fabrication costs, skin irritation, and the need for optimization in MN geometry and application methods persisted. Further research was needed to address these limitations and optimize MN patches for broader clinical use.
26 citations
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June 2020 in “Polymers” Microneedle made of iron oxide and PVA helps hair regrowth in alopecia treatment.
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August 2019 in “Dermatologic Therapy” Hair loss treatments work better with lifestyle changes.
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July 2018 in “Antioxidants” Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.
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March 2018 in “Journal of pharmacy & pharmaceutical sciences” Microneedles help improve drug delivery through the skin and are used in medicine and beauty treatments.
397 citations
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February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
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January 2021 in “Journal of Clinical Medicine” Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
August 2025 in “International Journal of Nanomedicine” Metal-organic frameworks can help heal wounds, reduce scars, and promote hair growth, but more research is needed.
48 citations
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July 2022 in “International Journal of Nanomedicine” Nanobiotechnology could improve chronic wound healing and reduce costs.
New hair regrowth therapies show promise but need more research.
47 citations
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July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
