The Effect of Microneedling on Skin Histology: Review of Literature

June 2024 in “ Annals of the College of Medicine Mosul/Annals of the College of Medecine ”

Harith Ali Hasan Al-Nauimi, Ashraf Alsamadi, Ahmed Hisham Qassim

microneedling fibroblast growth factor platelet-derived factor elastin collagen epidermal hyperplasia glycosaminoglycans alopecia actinic keratoses pigmentary disorders skin needling hair loss skin thickening skin rejuvenation

TLDR Microneedling safely improves skin by boosting collagen and elastin, helping with scars, stretch marks, and other skin issues.

Microneedling is a safe, effective, and low-cost technique for treating various dermatological disorders by mechanically inducing skin reconstruction. It involves using fine needles to create superficial skin perforations, which stimulate factors like fibroblast growth factor and platelet-derived factor, leading to the formation and reorganization of new elastin and collagen fibers. This process results in histological changes such as epidermal hyperplasia, dermal deposition of extracellular glycosaminoglycans, and increased elastic material in the dermis. Microneedling is recommended for conditions like facial scars, stretch marks, dyschromial conditions, photoaged skin rejuvenation, alopecia, actinic keratoses, and pigmentary disorders.

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