An Experimental Study: Microstructure of Hair Soft Tissue Filler Material and Its Clinical Application

January 2008

Zhang Qing-guo

hair microstructure soft tissue filler injectable hair material keratin fibroblasts collagen dermal augmentation biocompatibility

TLDR Hair material is a promising, safe, and effective soft tissue filler.

The study investigated the use of hair microstructure as a soft tissue filler material. After processing, the injectable hair material was tested on micropigs, and its effects were observed over 24 weeks. The results showed that the hair structure was largely retained, and there were no adverse reactions. Over time, the hair keratin was replaced by fibroblasts and collagen, with no significant fibromembrane formation. The treated dermis was thicker than the control, indicating significant dermal augmentation (p<0.05). The study concluded that hair material demonstrated good biocompatibility and effective dermal filling, suggesting its potential as a new soft tissue filler.

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