The Role of Microtrauma in Hair Regrowth and Regeneration in Non-Scarring Alopecia

Microtrauma, involving small, intentional skin injuries, is emerging as a promising method to stimulate hair growth in non-scarring alopecias by modulating immune responses. This review discusses the pathogenesis of hair loss and the mechanisms by which microtrauma can promote hair regrowth, such as through microneedling, lasers, contact immunotherapy, and platelet-rich plasma (PRP) injections. These procedures enhance hair growth by activating stem cells, increasing growth factor release, and improving blood circulation. In androgenetic alopecia, techniques like microneedling and PRP have shown efficacy in increasing hair density and thickness, while contact immunotherapy has been effective in alopecia areata. Although limited, studies on telogen effluvium suggest improvements in hair density with microneedling and PRP. Overall, microtrauma-based treatments offer promising strategies for hair regeneration, but further research is needed to optimize these therapeutic options for non-scarring alopecia.