Efficacy of 5% Topical Minoxidil Alone Versus Combination with Microneedling and PRP in Androgenetic Alopecia

The study compared the efficacy of 5% topical minoxidil monotherapy with a multimodal regimen combining minoxidil, microneedling, and autologous platelet-rich plasma (PRP) in treating androgenetic alopecia (AGA) in 50 patients aged 18-50. Group B, which received the combination treatment, showed significantly superior outcomes at 6 months compared to Group A, which received minoxidil alone. The study found that the combination treatment is more effective, although mild adverse effects like pruritus, seborrheic dermatitis, and headache were noted. The study concludes that PRP is a safe and effective adjunct, but further research with standardized protocols and larger studies is needed.