Machine Learning Driven Multi-Omics Analysis of the Genetic Mechanisms Behind the Double-Coat Fleece Formation in Hetian Sheep

    June 2025 in “ Frontiers in Genetics ”
    Yanwei Zhang, Wenrong Li, Xinming Xu, Mengxuan Xie, Liping Tang, Pai Zheng, Nannan Song, Li‐Juan Yu, Jiang Di
    TLDR Key genes IRF2BP2 and EGFR are linked to Hetian sheep's double-coat fleece.
    The study investigates the genetic mechanisms behind double-coated fleece formation in Hetian sheep, identifying key genes such as IRF2BP2 and EGFR. It highlights the use of machine learning-driven multi-omics analysis as a methodological approach, offering valuable insights for developing selection models in sheep breeding.
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