Questionnaire Modifications and Alternative Scoring Methods of the Dermatology Life Quality Index: A Systematic Review

This systematic review evaluated 59 modifications and alternative scoring methods of the Dermatology Life Quality Index (DLQI) across 77 studies involving 25,509 patients from 28 countries. The review found that many modifications lacked comprehensive validation, highlighting the need for further validation to ensure reliability and avoid biases in medical product labeling and reimbursement claims. The DLQI-R scoring and LY-DLQI questionnaire were identified as promising modifications for future validation. The review emphasized the importance of culturally adapted DLQI versions to better assess the quality of life impacts of dermatological conditions, including alopecia, on diverse patient populations.