TLDR New molecules involved in skin and hair growth were identified, improving understanding and future treatments.
The document reviewed classical and molecular histological studies on skin appendage morphogenesis, focusing on the cellular organization and molecular bases of skin appendage development. It highlighted the identification of new molecules expressed during the formation of skin appendages, such as growth factors, signaling molecules, and adhesion molecules, using feather and hair as models. The review aimed to provide groundwork for molecular mapping of skin appendages, enhancing understanding of developmental processes and potentially influencing future treatment modalities for healing and regeneration.
122 citations
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July 1994 in “Journal of Investigative Dermatology” 135 citations
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May 1994 in “Medical Entomology and Zoology” Mouse models help study genetic skin diseases.
67 citations
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February 1994 in “Developmental dynamics” Specific proteins and molecules play key roles in the development of human hair follicles.
578 citations
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April 1993 in “Cell” TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.
745 citations
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February 1992 in “Trends in genetics” Hair follicles create different cell layers and proteins, controlled by various molecules.
45 citations
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December 1991 in “Annals of the New York Academy of Sciences” Adhesion molecules are crucial for the development of feathers and hair.
45 citations
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December 1991 in “Annals of the New York Academy of Sciences” ECM molecules are crucial for hair growth and development.
33 citations
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September 1990 in “Proceedings of the National Academy of Sciences” The study showed that a specific DNA sequence can control gene expression in hair growth areas of mice.
356 citations
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December 1986 in “The journal of cell biology/The Journal of cell biology” Hair and nail cells share similar proteins, indicating a common differentiation pathway.
50 citations
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January 1986
