Mouse Hair Keratin cDNA: Implications and Sequences

    October 1988 in “ Clinics in Dermatology
    Arthur P. Bertolino
    TLDR Scientists identified and cloned specific keratin proteins in mouse hair.
    The document described a method for isolating mouse hair follicle mRNAs, identifying two peaks of mRNA activity at 11s and 18s. The larger mRNA group encoded keratins with molecular weights of 46K, 47K, 58K, 59K, and 63K. cDNAs were synthesized from these mRNAs and cloned to create a library, which revealed five acidic and six basic mouse hair keratin clones. This research was supported by several NIH grants and other foundations.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 167 results

      community My way to recovery and advice - Hope this helps (m20)

      in Product  6 upvotes 8 months ago
      A 20-year-old shared their experience of reversing hair loss without using minoxidil or finasteride, instead relying on supplements like biotin, collagen, fish oil, saw palmetto, and various vitamins. They emphasized the importance of a balanced supplement schedule and noted improvements in hair health without experiencing additional shedding.

      community Keratin microspheres - breakthrough

      in Research/Science  15 upvotes 1 year ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Natural Remedies: Polyphenols and Hair Loss

       20 upvotes 6 years ago
      Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

      community Results of Procyanidin B2 in clinical studies

      in Treatment  13 upvotes 5 years ago
      Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hair growth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.

    Related Research

    4 / 4 results