A Mouse Model for Conditional Expression of Activated Beta-Catenin in Epidermal Keratinocytes
August 2024
in “
Transgenic Research
”
Research cited in this study
8 / 8 resultsresearch Skin-Specific Transgenic Overexpression of Ovine β-Catenin in Mice
Overexpressing ovine β-catenin in mice skin increases hair follicle density and growth.
research Differential Sensitivity of Epidermal Cell Subpopulations to Beta-Catenin-Induced Ectopic Hair Follicle Formation
Sebaceous glands can form new hair follicles when activated, but hair follicle bulges cannot.
research The Hair Follicle as a Dynamic Mini-Organ
Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
research Embryonic Hair Follicle Fate Change by Augmented Beta-Catenin Through Shh and Bmp Signaling
β-catenin, Shh, and Bmp signaling control hair follicle development.
research Deciphering the Function of Canonical Wnt Signals in Development and Disease: Conditional Loss- and Gain-of-Function Mutations of β-Catenin in Mice
Wnt signaling is vital for cell growth, development, and cancer research.
research Activation of Beta-Catenin Signaling Programs Embryonic Epidermis to Hair Follicle Fate
Activating β-catenin can turn skin cells into hair follicles.
research Transient Activation of Beta-Catenin Signaling in Adult Mouse Epidermis Induces New Hair Follicles, Continuous Activation Maintains Tumors
Temporary activation of β-catenin can create new hair follicles, but ongoing activation is needed to keep hair follicle tumors.
research Conditional Gene Expression in the Epidermis of Transgenic Mice Using the Tetracycline-Regulated Transactivators tTA and rTA Linked to the Keratin 5 Promoter
The system allows precise control of gene expression in mouse skin, useful for studying skin biology.
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Different Myc family proteins are located in various parts of the hair follicle and may affect stem cell behavior.
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research Angora Mouse Mutation: Altered Hair Cycle, Follicular Dystrophy, Phenotypic Maintenance of Skin Grafts, and Changes in Keratin Expression
The angora mouse mutation causes long hair and hair defects due to a gene deletion.