Mesenchymal Stem Cells and Their Secretome: Candidates for Safe and Effective Therapy for Systemic Lupus Erythematosus

    September 2021 in “ Medical Journal of Cell Biology
    Małgorzata Popis, Aneta Konwerska, Małgorzata Partyka, Maria Wieczorkiewicz, Sylwia Ciesiółka, Katarzyna Stefańska, Julia Spaczyńska, Afsaneh Golkar‐Narenji, Michal Ješeta, Dorota Bukowska, Paul Mozdziak, Marta Dyszkiewicz-Konwińska
    TLDR Mesenchymal stem cells and their secretome may offer a safe and effective treatment for systemic lupus erythematosus.
    The document discussed the potential of mesenchymal stem cells (MSCs) and their secretome as therapeutic candidates for systemic lupus erythematosus (SLE). It highlighted that MSCs could modulate immune responses and promote tissue repair, making them promising for SLE treatment. The secretome of MSCs, which includes various bioactive molecules, was also noted for its therapeutic potential. The review emphasized the need for further research to confirm the safety and efficacy of MSC-based therapies in SLE, as well as to understand the mechanisms underlying their therapeutic effects.
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