Traumatization Of The Nasal Septum Mucosa In Rats Alters Behavior And Autonomic Nervous System Balance

    May 2022 in “ Голова и шея. ”
    И.В. Кастыро, В. И. Торшин, Г.В. Хамидулин, А.Н. Иноземцев, Е.В. Якшина, А.В. Роговая, Ф.П. Коврига, Н.Д. Рябухина, С.С. Шилин
    The study demonstrated that septoplasty simulation in 12 male rats led to changes in behavior and the autonomic nervous system, characterized by reduced exploratory activity and increased anxiety and depressive-like states. These behavioral changes were linked to postoperative stress, which was associated with metabolic, physiological, and morphological alterations in the hippocampal region. The research highlighted the impact of stress on neuron structure and cognitive functions, emphasizing the role of the hippocampus in these processes. Spectral analysis of heart rate variability was used to assess the autonomic nervous system, revealing shifts in parasympathetic and sympathetic activity post-surgery.
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