TLDR Intralesional corticosteroids effectively treat localized alopecia areata, often sparing white hairs.
A 55-year-old man presented with a 5.5 cm alopecic patch on the right temporal scalp, sparing white hairs, and was treated with intralesional triamcinolone acetonide, leading to regrowth of pigmented hair. The case highlights that intralesional corticosteroids are the first-line treatment for localized alopecia areata. The patient's hair regrowth pattern was treatment-specific, with initial regrowth of hypopigmented hairs. Alopecia areata is primarily a T cell-mediated autoimmune disease, targeting pigmented hairs and sparing white hairs, which explains the phenomenon of hair turning "white overnight."
1 citations
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April 2023 in “Clinical, cosmetic and investigational dermatology” Antigens from skin cells may cause hair loss in perinevoid alopecia.
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