New Therapeutic Strategies Based on the Use of Stem Cells for the Regeneration of Skin Lesions

The document reviews the potential of mesenchymal stem cell (MSC)-based therapies for regenerating skin lesions, particularly in chronic wounds where healing is impaired. MSCs are noted for their ability to modulate inflammation, promote angiogenesis, and enhance cellular proliferation, leading to improved wound closure rates, faster healing, increased collagen deposition, better re-epithelialization, and inflammation modulation. Despite these promising results, the studies reviewed are mostly preclinical or involve small sample sizes, highlighting the need for robust clinical trials and standardization to better assess the efficacy and safety of these therapies.